Amoxsan/Amoxsan Forte

Amoxicillin (Oral: Trihydrate; Inj: Na)

Lower resp tract infection. Typhoid & paratyphoid fever; typhoid carrier states. Gonorrhea. Uncomplicated UTI. Syphilis. Dental abscess. Otitis media.

Cap/Dispersible tab Adult & childn ≥20 kg 250-500 mg 8 hrly. Childn <20 kg 20-40 mg/kg 8 hrly in divided doses. Syr Childn >8 kg 125-250 mg 8 hrly. Paed drops All indications except infections of lower resp tract, Childn ≤6 mth 6-8 kg 0.5-1 mL 8 hrly, ≤6 kg 0.25-0.5 mL 8 hrly. Infections of lower resp tract Childn ≤6 mth 6-8 kg 1-1.5 mL 8 hrly, ≤6 kg 0.5-1 mL 8 hrly. Powd for inj Adult 250-500 mg IM 8 hrly. 500 mg-1 g IV/infusion 6 hrly in severe infections. Childn 35-100 mg/kg/day IM in divided doses or up to 100 mg/kg/day IV/infusion in divided doses 6 hrly over 30-min infusion. Typhoid & paratyphoid fever Adult 4 g daily in divided doses for 14-21 days. Childn 100 mg/kg/day in divided doses for 14-21 days. Typhoid carrier states 3-4 g daily in divided doses for min of 1 mth. Gonorrhea Single dose of 3 g + 1 g probenecid. Uncomplicated UTI Single dose of 3 g. Syphilis 250 mg 6 hrly for 4 wk up to 5 mth. Severe or recurrent lower resp tract infection 3 g twice daily. Dental abscess 3 g twice daily 8 hrly. Otitis media Adult & childn 3-10 yr 750 mg 2 times daily for 2 days.

May be taken with or without food: May be taken w/ meals for better absorption & to reduce GI discomfort.

Hypersensitivity to penicillins.

Periodically assess renal, hepatic & haematopoietic functions during prolonged therapy. Maintain adequate fluid intake & urinary output during high-dose treatment. Check indwelling catheters regularly for patency. Pregnancy & lactation.

Hypersensitivity, haematological & anaphylactoid reactions, GI disturbances.

Probenecid prolongs blood level of amoxicillin. Allopurinol increases incidence of skin rashes.

Penicillins

J01CA04 - amoxicillin ; Belongs to the class of penicillins with extended spectrum. Used in the systemic treatment of infections.

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